Puppy Care

Puppy Vaccination Schedule: What Each Shot Does

From DHPP to rabies, understand every vaccine your puppy needs and why timing matters for immunity.

By Lucas Martin · Published 18 October 2026
Puppy Vaccination Schedule: What Each Shot Does

The Core Vaccination Schedule

Puppies receive maternal antibodies from their mother's milk, which gradually fade between 6-16 weeks. Vaccinations must be timed after these antibodies drop but before the puppy is vulnerable to disease.

The 6-8 Week Vaccines

First DHPP (Distemper, Hepatitis, Parainfluenza, Parvovirus). This is the starting point — maternal antibodies are fading and the puppy's own immune system needs to begin building protection.

The 10-12 Week Boosters

Second DHPP plus often Leptospirosis. The booster reinforces the immune response started at 6-8 weeks. Most vets recommend keeping puppies away from public areas until 2 weeks after this booster.

The 14-16 Week Final Round

Final DHPP, Leptospirosis booster, and Rabies (required by law in most areas). After 2 weeks from this final set, your puppy is considered fully protected and can safely visit parks and meet other dogs.

  • Keep a vaccination record — boarding kennels and groomers will ask for it
  • Mild lethargy after vaccination is normal; contact your vet if it lasts over 48 hours
  • Annual boosters maintain immunity — mark your calendar
  • Titre testing can check immunity levels in adult dogs as an alternative to annual boosters
Written by

Lucas Martin

All our authors care for dogs every day — read more of their work on the authors page.